Endocrine Abstracts

The aim of this study is to report a case of an unusual presentation of anaplastic thyroid carcinoma and describe its clinical, radiological and management particularities. Observation: We report the case of a 60 year-old female patient who presented with a two-week history of progressive aphagia, associated with hemoptysis. She also described recent shortness of breath, and a painless cervical mass evolving for 10 months, rapidly enlarging during the last four weeks. Her medi...

Introduction: Cushing’s disease is characterized by an endogenous hypercortisolism related to a pituitary adenoma, its association with an empty sella turcica is exceptionally rare.Case report: A 55 year old diabetic patient with hypertension was admitted for investigation of Cushing’s syndrome. Clinical examination found facial and truncal obesity with facial erythrosis, capillary fragility with multiple ecchymoses, proximal amyotrophy of the ...

Introduction: The association of papillary carcinoma with medullary thyroid carcinoma may in rare cases be found in some members of families with multiple endocrine neoplasia type 2a (MEN 2a).Case Report: A 38-year-old patient with a family history of papillary thyroid carcinoma (PTC), operated for multinodular goiter classified Tirads 4 by total thyroidectomy, the anatomopathological examination concluded to a lobar medullary thyroid carcinoma (MTC) of ...

Introduction: Pituitary apoplexy (PA) is a rare incident defined by the occurrence of necrosis and/or haemorrhage of the pituitary gland. PA is a clinical syndrome characterized by the sudden onset of headache, vomiting, visual impairment and decreased consciousness in some cases. The objectives of our study are to describe its clinical, biological and imaging features as well as the management of PA in the region of Sfax.Patients and methods: It is a re...

Objective: To highlight an unusual cause of hyperinsulinaemic hypoglycemiaMethods: Case Report: Results or Case PresentationA previously healthy and fit 52 year old gentleman of Asian descent presented with recurrent severe neuroglycopenic hyperinsulinemic hypoglycemic symptoms, suggestive of insulinoma. On several occasions he was confirmed to have severe hypoglcaemia with venous blood glucose values ranging between 1.5 and 2.7 mm...

Introduction: Irisin is a myokin secreted by myocytes responsible for transmission of signals from muscles to other body tissues. It improves systemic metabolism by increasing energy expenditure and has a significant influence on the body metabolism and thermogenesis. Thyroid disorders are characterized by a disrupted thermo-metabolic state and muscular damage, and the underlying mechanisms still not clear.Aim: To evaluate serum Irisin levels in patient ...

Introduction: Vitamin D plays an essential role in calcium homeostasis and bone metabolism, immune modulation, and control of other hormonal systems. Vitamin D deficiency is also common for many reasons. On the other hand, thyroid diseases have widespread systemic manifestations including their effect on bone metabolism.Aim: To assess vitamin D status among Egyptian patients with different thyroid states: euthyroid, hypothyroid, or hyperthyroid states.</...

Content: Type 2 diabetes mellitus (T2DM) may be associated with disorders in innate immune system. Toll-like receptor 2 (TLR2) is an important mediator of the innate immunity with subsequent proinflammatory reactions that thought to be involved in the cardiovascular complications in T2DM.Objective: We evaluate the role of TLR2 in T2DM patients with cardiovascular complications.Patients and methods: The study was conducted on 60 pat...

Introduction: Thyroid nodules are extremely common. By age 60, about one-half of all people have a thyroid nodule. Cryoablation is used in a variety of clinical applications, using hollow needles (cryoprobes). Cryoprobes are inserted into or placed adjacent to diseased tissue which is desired to be ablated.Objectives: To evaluate the effect of Cryoablation on the size & function of thyroid nodule, which may replace the need for surgery or radiotherap...

Introduction: The magnesium deficiency is frequently associated with diabetes mellitus, it is also incriminated in the occurrence of diabetic complications (micro and macrovascular). Our objective was to study the correlation between magnesium deficiency (Mg) and the presence of chronic diabetic complications.Material and methods: Prospective study that concerned type 2 diabetics (T2D). Our patients were subdivided into 2 groups G1 and G2: G1 including 1...